Ski3 Polyclonal Antibody
Catalogue Number: BS-53094R-BSS
BS-53094R Image
BS-53094R Image
BS-53094R Image
Western blot was performed on HeLa nuclear extracts (lane 1) and purified human SKI complex (lane 2) (Figure A), or on nuclear extracts from HeLa cells (HeLa NE, 20 µg) (Figure B) using the Bioss antibody against SKI3 (Cat. No. bs-53094R) diluted 1:1,000.
BS-53094R Image
HeLa cells were stained with the Bioss antibody against SKI3 (Cat. No. bs-53094R) (red), with DAPI to label the DNA (blue), and with an antibody against α-tubulin to label the cytoplasm (green). SKI3 is detected in both the cytoplasm and the nucleus but appears to be excluded from the nucleolus.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Preservative: | 0.05% Sodium azide; ProClin™ 300 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Antiviral protein SKI8, SKI8, Superkiller protein 8, REC103 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 150 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | Polyclonal antibody raised in rabbit against human SKI3, using a recombinant protein |
| Application: | ICC, IF, WB |
Description
Description: Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes. Also component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology.
Additional Text
Gene Name
SKI8
Uniprot ID
Q02793
Purification
Protein G purified
Antibody Clonality
Polyclonal
Concentration
3 ug/ul
Gene ID
852659
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bs-53094R Datasheet
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