SOX2 (7C4) Monoclonal Antibody
Catalogue Number: BSM-51142M-BSS
BSM-51142M Image
BSM-51142M Image
BSM-51142M Image
BSM-51142M Image
BSM-51142M Image
bsm-51142M Image
BSM-51142M Image
Lane 1: SOX2 Protein Isolate; probed with SOX2 (7C4) Monoclonal Antibody, unconjugated (bsm-51142M) at 1:4000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-51142M Image
IF(ICC) staining with SOX2 (7C4) Monoclonal Antibody (bsm-51142M) at 1:50 (37°C for 1hr) in A549 cells (green). Cells were counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin. Cells were fixed in 4% paraformaldehyde for 20min and permeabilized with 0.1% Triton X100/PBS for 10min.
BSM-51142M Image
Paraformaldehyde-fixed and paraffin-embedded Human Lung Cancer tissue incubated with SOX2 (7C4) Monoclonal Antibody (bsm-51142M) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-51142M Image
Lane 1: 293 Cells nontransfected; Lane 2: 293 Cells transiently transfected with SOX2 gene; Lane 3: Mouse Testis; Probed with SOX2 (7C4) Monoclonal Antibody (bsm-51142M) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-51142M Image
Flow cytometric analysis of NCI-H460 cells with SOX2 (7C4) Monoclonal Antibody (bsm-51142M) at a 1:50 dilution (red) compared with a negative control (cells without incubation with primary antibody; blue).
bsm-51142M Image
NCCIT cell lysate probed with bsm-51142M SOX2 (7C4) Monoclonal Antibody at 1:1000 dilution and 4℃ overnight incubation, followed by secondary antibody incubation for 60min at room temperature.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Preservative: | 0.09% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Transcription factor SOX-2; SOX2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 7C4 |
| Isotype: | IgG1 |
| Immunogen: | SOX2 recombinant protein |
| Application: | FC, ICC, IF, IHC-P, WB |
Description
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.
Additional Text
Gene Name
SOX2
Gene ID
6657
Purification
Protein G purified
Uniprot ID
P48431
Concentration
0.5 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-51142M Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations