FMR1 (8C2) Monoclonal Antibody

Catalogue Number: BSM-51162M-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Preservative:0.09% Sodium azide
Type:Monoclonal Primary Antibody - Unconjugated
Alias:POF; FMRP; POF1; FRAXA; Synaptic functional regulator FMR1; Fragile X mental retardation protein 1; Protein FMR-1; FMR1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 8C2
Isotype: IgM
Immunogen: This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.
Application: WB

Description

Description: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Additional Text

Gene Name

FMR1

Uniprot ID

Q06787

Gene ID

2332

Concentration

0.5 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C for 12 months.