KLF4 (5A1) Monoclonal Antibody

Catalogue Number: BSM-51264M-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Preservative:0.09% Sodium azide
Type:Monoclonal Primary Antibody - Unconjugated
Alias:EZF; GKLF; Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor; KLF4
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 5A1
Isotype: IgG1
Immunogen: KLF4 recombinant protein is used to produce this monoclonal antibody.
Application: ICC, IF, WB

Description

Description: Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Additional Text

Gene Name

KLF4

Gene ID

9314

Uniprot ID

O43474

Purification

Protein A purified

Concentration

0.5 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.