COX1/Cyclooxygenase 1 (4A8) Monoclonal Antibody

Catalogue Number: BSM-52569R-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Prostaglandin G/H synthase 1, Cyclooxygenase-1, Prostaglandin H2 synthase 1, Prostaglandin-endoperoxide synthase 1, COX-1, PGH synthase 1, PGHS-1, PHS 1, PTGS1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: 4A8
Isotype: IgG
Immunogen: Human COX1/ Cyclooxygenase 1 between 400 to 600 amino acids
Application: FC, ICC, IF, IHC-P, WB, IHC

Description

Description: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Additional Text

Gene Name

PTGS1

Uniprot ID

P23219

Gene ID

5742

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C for 12 months.