Catalogue Number: BSM-52569R-BSS
Manufacturer: | Bioss Inc |
Shelf Life: | 12 months |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Prostaglandin G/H synthase 1, Cyclooxygenase-1, Prostaglandin H2 synthase 1, Prostaglandin-endoperoxide synthase 1, COX-1, PGH synthase 1, PGHS-1, PHS 1, PTGS1 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Rabbit |
Clone: | 4A8 |
Isotype: | IgG |
Immunogen: | Human COX1/ Cyclooxygenase 1 between 400 to 600 amino acids |
Application: | FC, ICC, IF, IHC-P, WB, IHC |
Description: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
PTGS1
P23219
5742
Protein A purified
1 ug/ul
Monoclonal
Unmodified
Store at -20°C for 12 months.