Human CCR7 Protein-Nanodisc (CCR-HM107)
Catalogue Number: CCR-HM107-KAT
CCR-HM107 Image
CCR-HM107 Image
CCR-HM107 Image
Human CCR7 (Nanodisc), His Tag captured on CM5 Chip via Anti-his antibody can bind Anti-CCR7 Antibody, hFc Tag with an affinity constant of 4.11 nM as determined in SPR assay (Biacore T200).
CCR-HM107 Image
Immobilized Human CCR7 (Nanodisc), His Tag at 1µg/ml (100µl/well) on the plate. Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 0.21µg/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 67.70 kDa. |
| Physical state: | Liquid |
| Type: | Fusion Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA |
Description
Description: CC-chemokine receptor 7 (CCR7), collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal expression of CCR7 in dendritic cells will cause a series of inflammatory diseases due to the chaotic dendritic cell trafficking.
Additional Text
Gene ID
1236
Gene Name
CCR7
Uniprot ID
P32248
Protein Tag
HIS Tag
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Short Description
Recombinant Human CCR7 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Pro378.
CCR-HM107 Datasheet
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