Human CD20 Protein-VLP (CD2-HM122)
Catalogue Number: CD2-HM122-KAT
CD2-HM122 Image
CD2-HM122 Image
CD2-HM122 Image
CD2-HM122 Image
CD2-HM122 Image
The purity of Human CD20 VLP is greater than 95% as determined by SEC-HPLC.
CD2-HM122 Image
Immobilized Human CD20 VLP at 5µg/ml (100µl/Well) on plate on the plate. Dose response curve for Rituximab, hFc Tag with the EC50 of 11.4ng/ml determined by ELISA (QC Test).
CD2-HM122 Image
Immobilized Human CD20 VLP at 5µg/ml (100µl/Well) on plate on the plate. Dose response curve for Ofatumumab, hFc Tag with the EC50 of 10.5ng/ml determined by ELISA (QC Test).
CD2-HM122 Image
Immobilized Human CD20 VLP at 5µg/ml (100µl/well) on the plate. Dose response curve for Obinutuzumab, hFc Tag with the EC50 of 1.7ng/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The target protein has a predicted MW of 34.3 kDa. |
| Physical state: | Liquid |
| Type: | Other Proteins |
| Alias: | MS4A1; CD20; MS4A-1; B1; Bp35; CD20 receptor; CD20S7; CVID5; LEU-16; Ly-44; MS4A2; S7 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA |
Description
Description: B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.
Additional Text
Short Description
Recombinant Human CD20 Protein-VLP is expressed from HEK293.It contains Met1-Pro297.
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
UniProt ID
P11836-1
CD2-HM122 Datasheet
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