Biotinylated Human CD20 Protein-VLP (CD2-HM122B)
Catalogue Number: CD2-HM122B-KAT
CD2-HM122B Image
CD2-HM122B Image
CD2-HM122B Image
CD2-HM122B Image
Biotinylated Human CD20 VLP, captured on CM5 Chip via streptavidin can bind Rituximab, hFc Tag with an affinity constant of 0.68 nM as determined in SPR assay (Biacore T200) (QC Test).
CD2-HM122B Image
Biotinylated Human CD20 VLP captured on CM5 Chip via streptavidin can bind Ofatumumab, hFc Tag with an affinity constant of 0.61 nM as determined in SPR assay (Biacore T200).
CD2-HM122B Image
The purity of Biotinylated Human CD20 VLP is greater than 95% as determined by SEC-HPLC.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The target protein has a predicted MW of 34.3 kDa. |
| Physical state: | Liquid |
| Type: | Protein - Conjugated |
| Alias: | MS4A1; CD20; MS4A-1; B1; Bp35; CD20 receptor; CD20S7; CVID5; LEU-16; Ly-44; MS4A2; S7 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ul |
Description
Description: B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.
Additional Text
Short Description
Recombinant Biotinylated Human CD20 Protein-VLP is expressed from HEK293.It contains Met1-Pro297.
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
UniProt ID
P11836-1
CD2-HM122B Datasheet
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