Human CD3E&CD3D/CD3 epsilon&CD3 delta Protein (CD3-HM205)
Catalogue Number: CD3-HM205-KAT
CD3-HM205 Image
CD3-HM205 Image
CD3-HM205 Image
CD3-HM205 Image
CD3-HM205 Image
CD3-HM205 Image
Immobilized Human CD3E&CD3D, hFc Tag at 0.5µg/ml (100µl/Well). Dose response curve for Biotinylated Anti-CD3E&CD3D Ab.1, hFc Tag with the EC50 of 31.68ng/ml determined by ELISA.
CD3-HM205 Image
Immobilized Human CD3E&CD3D, hFc Tag at 1µg/ml (100ul/Well). Dose response curve for Anti-CD3E&CD3D Ab.2, mFc Tag with the EC50 of 45.9ng/ml determined by ELISA (QC Test).
CD3-HM205 Image
Immobilized Tebentafusp, His Tag at 1µg/ml (100µl/well) on the plate. Dose response curve for Human CD3E&CD3D, hFc Tag with the EC50 of 8.7ng/ml determined by ELISA.
CD3-HM205 Image
The purity of Human CD3E&CD3D was greater than 95% as determined by SEC-HPLC.
CD3-HM205 Image
Human CD3E&CD3D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 37.8 kDa (CD3E) and 35.4 kDa (CD3D). Due to glycosylation, the protein migrates to 48-58 kDa (CD3E) and 42-48 kDa (CD3D) based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | CD3; CD3e; CD3E; CD3d; T3D; CD3D; CD3E&CD3D; CD3 delta&CD3 epsilon |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Additional Text
Protein Tag
hFC Tag
UniProt ID
P04234, P07766
Gene ID
915; 916
Gene Name
CD3D, CD3E
Short Description
Recombinant Human CD3E&CD3D/CD3 epsilon&CD3 delta Protein is expressed from HEK293 with hFc at the C-Terminus.It contains Asp23-Asp126(CD3E)&Phe22-Ala105(CD3D).
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
CD3-HM205 Datasheet
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