Catalogue Number: CD3-MM205-KAT
Manufacturer: | Kactus |
Shelf Life: | 12 months |
Molecular Weight: | The protein has a predicted MW of 36.1 kDa (CD3E) and 35.2 kDa (CD3D). Due to glycosylation,the protein migrates to 50-65 kDa and 40-50 kDa based on Tris-Bis PAGE result. |
Physical state: | Lyophilized |
Type: | Fusion Protein |
Alias: | CD3; CD3e; CD3E; CD3d; T3D; CD3D; CD3E&CD3D; CD3 delta&CD3 epsilon |
Host Cell: | HEK293 cells |
Shipping Condition: | RT |
Unit(s): | 100 ug, 500 ug |
Application: | WB |
Description: T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
hFC Tag
P04235, P22646
CD3D, CD3E
12500; 12501
Recombinant Mouse CD3E&CD3D/CD3 epsilon&CD3 delta Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp23-Asp108(CD3E)&Phe22-Ala105(CD3D).
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.