Human CDH17/Cadherin 17 Protein (CDH-HM117)
Catalogue Number: CDH-HM117-KAT
CDH-HM117 Image
CDH-HM117 Image
CDH-HM117 Image
CDH-HM117 Image
The purity of Human CDH17 is greater than 95% as determined by SEC-HPLC.
CDH-HM117 Image
Human CDH17 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
CDH-HM117 Image
Immobilized Human CDH17, His Tag at 0.5 µg/ml (100 µl/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 6.0 ng/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 86.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result. |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Additional Text
Protein Tag
HIS Tag
Uniprot ID
Q12864-1
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Short Description
Recombinant Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.; It contains Gln23 - Met787.
CDH-HM117 Datasheet
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