Human Claudin 4 Protein-VLP (CLD-HM104)
Catalogue Number: CLD-HM104-KAT
CLD-HM104 Image
CLD-HM104 Image
CLD-HM104 Image
Immobilized Human Claudin 4 VLP at 1µg/ml (100µl/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.
CLD-HM104 Image
The purity of Human Claudin 4 VLP is greater than 95% as determined by SEC-HPLC.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The target protein has a predicted MW of 23.31 kDa. |
| Physical state: | Liquid |
| Type: | Other Proteins |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA |
Description
Description: Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
Additional Text
Gene ID
1364
Gene Name
CLDN4
Uniprot ID
O14493
Short Description
Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
CLD-HM104 Datasheet
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