JBS Bright Red

Catalogue Number: CO-304-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Type:Biological dyes
Shipping Condition:RT
Storage Condition:RT
Unit(s): 300 ul

Description

Description: Crystallization screening with high concentrations of precipitant and salt may lead to the formation of salt crystals. It is quite difficult to make a distinction between these false positives and true protein crystals. Staining of crystals with appropriate dyes is a very straightforward method to differentiate between macromolecular crystals and salt crystals [1]. Protein and salt crystals differ substantially in their solvent content. Small crystal dyes, like JBS Bright Red, are able to permeate the solvent channels of a protein, thus coloring the protein red. In contrast, salt crystals are tightly packed and do not possess large solvent channels. They will therefore remain colourless.

Additional Text

Application Notes

JBS Bright Red is a crystal dye used to stain macromolecular crystals, i.e. protein, peptide and nucleic acid crystals in order to differentiate them from small molecules and salt crystals.

Short Description

Eosin Scarlet

Molecular Weight

624.08 g/mol

CAS Number

548-24-3

Molecular Formula

C20H6Br2N2Na2O9

Smile String

c1(c(cc2c(c1Br)Oc1c(C32c2ccccc2C(=O)O3)cc(c(c1Br)[O-])[N+](=O)[O-])[N+](=O)[O-])[O-].[Na].[Na]