Catalogue Number: CO-304-JEN
Manufacturer: | Jena Bioscience |
Shelf Life: | 12 months |
Type: | Biological dyes |
Shipping Condition: | RT |
Storage Condition: | RT |
Unit(s): | 300 ul |
Description: Crystallization screening with high concentrations of precipitant and salt may lead to the formation of salt crystals. It is quite difficult to make a distinction between these false positives and true protein crystals. Staining of crystals with appropriate dyes is a very straightforward method to differentiate between macromolecular crystals and salt crystals [1]. Protein and salt crystals differ substantially in their solvent content. Small crystal dyes, like JBS Bright Red, are able to permeate the solvent channels of a protein, thus coloring the protein red. In contrast, salt crystals are tightly packed and do not possess large solvent channels. They will therefore remain colourless.
JBS Bright Red is a crystal dye used to stain macromolecular crystals, i.e. protein, peptide and nucleic acid crystals in order to differentiate them from small molecules and salt crystals.
Eosin Scarlet
624.08 g/mol
548-24-3
C20H6Br2N2Na2O9
c1(c(cc2c(c1Br)Oc1c(C32c2ccccc2C(=O)O3)cc(c(c1Br)[O-])[N+](=O)[O-])[N+](=O)[O-])[O-].[Na].[Na]