Recombinant Human Sonic hedgehog protein(SHH), partial (Active)

Catalogue Number: CSB-AP000371HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:19.8 kDa
Physical state:Lyophilized
Type:Proteases
Alias:SHH
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 5 ug, 500 ug

Description

Description: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity). {ECO:0000250}.

Additional Text

Uniprot ID

Q15465

OMIN ID

135750

Protein Tag

Untagged

Price
£697.00


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