Catalogue Number: CSB-AP002591HU-CSB
Manufacturer: | Cusabio Biotech |
Shelf Life: | 6 months |
Molecular Weight: | 19.3 kDa |
Physical state: | Lyophilized |
Type: | Growth Factors |
Alias: | VEGF-A, VPF |
Host Cell: | Yeast |
Shipping Condition: | Blue Ice |
Unit(s): | 10 ug, 100 ug, 500 ug |
Description: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. {ECO:0000269|PubMed:11427521, ECO:0000269|PubMed:16489009}.
P15692
192240
Untagged