Recombinant Human Transforming growth factor beta-1 proprotein(TGFB1), partial (Active)
Catalogue Number: CSB-AP003861HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 12.8 kDa |
| Physical state: | Lyophilized |
| Type: | Transforming Growth Factors |
| Alias: | Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB |
| Host Cell: | Mammalian Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 10 ug, 50 ug, 500 ug |
Description
Description: Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
Additional Text
Uniprot ID
P01137
OMIN ID
131300
Protein Tag
Untagged
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