Recombinant Human Corticotropin-releasing factor receptor 1 (CRHR1), partial
Catalogue Number: CSB-EP005965HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 37.9 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Fusion Protein |
| Alias: | Corticotropin-releasing hormone receptor 1 ;CRH-R-1 ;CRH-R1 |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 20 ug |
Description
Description: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal bryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
Additional Text
Uniprot ID
P34998
Protein Tag
GST Tag
OMIN ID
122561
CSB-EP005965HU Protocol
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