ANPEP Antibody

Catalogue Number: CSB-PA001827LA01HU-CSB

Manufacturer:Cusabio Biotech
Preservative:0.03% ProClin™ 300
Ph:7.4
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant Human Aminopeptidase N protein (34-219AA)
Application: ELISA, IF, WB, IHC

Description

Description: Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.

Additional Text

Gene ID

290

Gene Name

ANPEP

Uniprot ID

P15144

Purification

Protein G purified

Antibody Clonality

Polyclonal

Specificity

Alanyl (membrane) aminopeptidase antibody; Alanyl aminopeptidase antibody; Aminopeptidase M antibody; Aminopeptidase N antibody; AMPN_HUMAN antibody; ANPEP antibody; AP M antibody; AP N antibody; AP-M antibody; AP-N antibody; APN antibody; CD 13 antibody; CD13 antibody; CD13 antigen antibody; gp150 antibody; hAPN antibody; LAP 1 antibody; LAP1 antibody; Microsomal aminopeptidase antibody; Myeloid plasma membrane glycoprotein CD13 antibody; p150 antibody; PEPN antibody