Catalogue Number: CSB-PA333052LA01BJO-CSB
Manufacturer: | Cusabio Biotech |
Preservative: | 0.03% ProClin™ 300 |
Ph: | 7.4 |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | S antibody; 3 antibody; Spike glycoprotein antibody; S glycoprotein antibody; E2 antibody; Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2'] antibody |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 50 ug |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Recombinant Bovine coronavirus Spike glycoprotein protein (326-540AA) |
Application: | ELISA |
Description: S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.By similarity S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes (By similarity).
Protein G purified
P25194
Polyclonal