PKC-412 (Midostaurin)
Catalogue Number: CV-1004-2-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Kinase Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 5 mg |
Description
Description: Pan-specific kinase inhibitor. Selectively induces G1 arrest and apoptosis in Ba/F3 cells expressing mutant FLT3, IC50<10 nM. FLT3 ligand impedes the efficacy of inhibition by PKC-412. Potential therapeutic use in pancreatic cancer. Cell permeable. Active in vivo.
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