Apicidin

Catalogue Number: CV-1013-2-RPE

Manufacturer:rPeptide
Physical state:Lyophilized
Type:Enzyme Inhibitors
Shipping Condition:RT
Unit(s): 5 mg

Description

Description: Cyclopeptide inhibitor of histone deacetylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-100 nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1a protein levels and transcriptional activity in human and mouse tumor cell lines. Cell permeable.