DTG
Catalogue Number: CV-1040-2-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Biochemicals |
| Shipping Condition: | RT |
| Unit(s): | 500 mg |
Description
Description: DTG is a high affinity agonist of the sigma (σ) receptor with roughly equal potency against both subtypes (σ1 and σ2 IC50's ~ 30 nM). Induces heavy alcohol drinking in rats in a model of alcohol use disorder. Increases BDNF expression and attenuates ischemia/reperfusion-induced learning impairment in mouse models.
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