Cathepsin B Polyclonal Antibody

Catalogue Number: E-AB-13973-ELA

Manufacturer:	Elabscience
Preservative:	0.05% Sodium azide
Ph:	7.3
Type:	Polyclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	120 ul, 20 ul, 60 ul, 200 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Recombinant protein of human CTSB
Application:	ELISA, IHC

Overview
Datasheets

Description

Description: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

Additional Text

Uniprot ID

P07858

Concentration

0.3 mg/ml

Purification

Affinity Purified

Accession Number

BC010240

Specificity

Amyloid precursor protein secretase,APP secretase,APPS,CATB,Cathepsin B heavy chain,Cathepsin B1,CathepsinB,CPSB,CTSB,cysteine protease,OTTHUMP00000116009,OTTHUMP00000229510,OTTHUMP00000229511,OTTHUMP00000229512,OTTHUMP00000229514,OTTHUMP00000229515,OTTHUMP00000229516,Preprocathepsin B

Antibody Clonality

Polyclonal

Store at -20°C. Avoid freeze / thaw cycles.

E-AB-13973 Protocol

Price

£154.00

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