CD10 Polyclonal Antibody
Catalogue Number: E-AB-15992-ELA
E-AB-15992 Image
E-AB-15992 Image
E-AB-15992 Image
Immunohistochemistry of paraffin-embedded Human brain tissue using CD10 Polyclonal Antibody at dilution 1:85
E-AB-15992 Image
Immunohistochemistry of paraffin-embedded Human kidney tissue using CD10 Polyclonal Antibody at dilution of 1:100(Elabscience® Product Detected by Lifespan).
| Manufacturer: | Elabscience |
| Preservative: | 0.05% Sodium azide |
| Ph: | 7.3 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 120 ul, 20 ul, 60 ul, 200 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of human MME |
| Application: | ELISA, IHC |
Description
Description: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.
Additional Text
Uniprot ID
P08473
Accession Number
NP_000893
Concentration
0.5 mg/ml
Purification
Affinity Purified
Specificity
Atriopeptidase,CALLA,CD10,CD10 antigen,Common acute lymphocytic leukemia antigen,DKFZp686O16152,EC 3.4.24.11,Enkephalinase,EPN,Membrane metallo endopeptidase (neutral endopeptidase,enkephalinase),Membrane metallo endopeptidase (neutral endopeptidase,enkephalinase,CALLA,CD10),Membrane metallo endopeptidase,Membrane metallo endopeptidase variant 1,Membrane metallo endopeptidase variant 2,Membrane metalloendopeptidase,Membrane metalloendopeptidase neutral endopeptidase enkephalinase,Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10,Membrane metalloendopeptidase variant 1,Membrane metalloendopeptidase variant 2,MGC126681,MGC126707,MME,NEP,NEP,Neprilysin,neprilysin-390,neprilysin-411,Neutral endopeptidase 24.11,Neutral endopeptidase,Neutral endopeptidase,membrane-associated,SFE,Skin fibroblast elastase
Antibody Clonality
Polyclonal
Store at -20°C. Avoid freeze / thaw cycles.
E-AB-15992 Protocol
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