IL6R Polyclonal Antibody

Catalogue Number: E-AB-40344-ELA

Manufacturer:Elabscience
Preservative:0.05% ProClin™ 300
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 120 ul, 20 ul, 200 ul, 60 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant Human Interleukin-6 receptor subunit alpha protein
Application: WB, IHC

Description

Description: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Additional Text

Concentration

1 mg/ml

Uniprot ID

P08887

Purification

Affinity Purified

Specificity

CD 126,CD126,CD126 antigen,gp80,IL 6R 1,IL 6R alpha,IL 6R,IL-6 receptor alpha chain,IL-6 receptor subunit alpha,IL-6R 1,IL-6R subunit alpha,IL-6R-alpha,IL-6RA,IL6Q,Il6r,IL6RA,IL6RA,IL6RQ,Interleukin 6 receptor,interleukin 6 receptor,alpha,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80,MGC30256

Antibody Clonality

Polyclonal

Store at -20°C. Avoid freeze / thaw cycles.

Price
£147.00


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