(KO Validated) NCOA2 Polyclonal Antibody
Catalogue Number: E-AB-63329-ELA
E-AB-63329 Image
E-AB-63329 Image
E-AB-63329 Image
E-AB-63329 Image
Western blot analysis of extracts of various cell lines using NCOA2 Polyclonal Antibody at dilution of 1:1000.
E-AB-63329 Image
Western blot analysis of extracts from normal (control) and NCOA2 knockout (KO) 293T cells using NCOA2 Polyclonal Antibody at dilution of 1:1000.
E-AB-63329 Image
Immunohistochemistry of paraffin-embedded Rat brain using NCOA2 Polyclonal Antibody at dilution of 1:100 (40x lens).
| Manufacturer: | Elabscience |
| Preservative: | 0.02% Sodium azide |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | NCOA2,GRIP1,KAT13C,NCoA-2,SRC2,TIF2,bHLHe75 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 120 ul, 200 ul, 60 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein of human NCOA2 (NP_006531.1). |
| Application: | WB, IHC |
Description
Description: The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants.
Additional Text
Concentration
1 mg/ml
Gene ID
10499
Gene Name
NCOA2
Uniprot ID
Q15596
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Store at -20°C. Avoid freeze / thaw cycles.
E-AB-63329 Protocol
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