APC Anti-Mouse CD8a Antibody[53-6.7]
Catalogue Number: E-AB-F1104E-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests, 200 Tests, 50 tests |
| Host name: | Rat |
| Clone: | 53-6.7 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Additional Text
Gene Name
CD8A
Gene ID
12525
Uniprot ID
P01731
Antibody Clonality
Monoclonal
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
E-AB-F1104E Protocol
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