STEALTH Liposomal Irinotecan HCl (2.0mg/mL)

Catalogue Number: F30204-IT-FOR

Manufacturer:	FormuMax
Type:	Liposome
Alias:	STEALTH Liposomal Irinotecan HCl (2.0mg/mL) (F30204-IT)
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	2 ml, 10 ml

Overview

Description

Description: PEGylated Liposomal Irinotecan HCl Irinotecan HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) with ammonium gradient by the active loading approach. The liposomes are produced by the extrusion method. The product is of high quality with narrow particle size distribution and high drug encapsualtion efficiency. Product For Research only and NOT for Human Use Specifications Product code: F30204S-IT Lipid composition: HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Lipid concentration: 20.0 mM Iroinotecan HCl: 2.0 mg/mL Encapsulation efficiency: > 95% (typically 98%) Loading battery: 250 mM ammonium sulfate Mean particle size: 100 nm (80-110 nm) External solution: 10% sucrose, 20 Mm HEPES, pH 7.0 Shelf-life: 3 months, storage: 2-8 degree C Irinotecan: Synonym: (S),Aea-,Aea4,11-,Aeadiethyl-,Aea3,4,12,14-,Aeatetrahydro-,Aea4-,Aeahydroxy-,Aea3,14-,Aeadioxo-,Aea1H-,Aeapyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester, CPT-11, [1,4'-Bipiperidine]-1'-carboxylic acid CAS Number 100286-90-6, Empirical Formula: C33H38N4O6 . HCl, Sigma Cat# I1406 HSPC: hydrogenated phosphatidylcholine (Soy) CHOL: cholesterol mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

Price

£1,106.00

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