Catalogue Number: F30204B-D2-FOR
Manufacturer: | FormuMax |
Type: | Liposome |
Shipping Condition: | Blue Ice |
Storage Condition: | 2-8°C |
Unit(s): | 10 ml, 2 ml |
Description: Doxoves® - PEGylated Liposomal Doxorubicin HCl (2.0mg/mL) Doxorubicin HCl is loaded into PEGylated liposomes with ammonium gradient by the active loading approach. It is comparable to the commercial product DOXIL®/Caelyx® at 2.0mg/mL drug concentration. The liposomes are prepared to high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency. Note we also carry a high drug concentration (4.0 mg/mL) version of this product (F30204B). Control liposomes for this product: F30204B-C2 Product For Research only and NOT for Human Use Specifications Product code: F30204B-D2 Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) Lipid concentration: 20.0 mM Doxorubicin HCl: 2.0 mg/mL Encapsulation efficiency: > 95% (typically 98%) Loading battery: 250 mM ammonium sulfate Mean particle size: 85 nm (80 - 90 nm) External solution: 10% sucrose, 10 mM histidine, pH 6.5 Shelf-life: 6 months, storage: 2-8 degree C HSPC: hydrogenated phosphatidylcholine (Soy) CHOL: cholesterol mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]