Human GDF15 Protein (GDF-HM215)

Catalogue Number: GDF-HM215-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Physical state:Lyophilized
Type:Cytokines
Alias:GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.

Additional Text

Gene ID

9518

Uniprot ID

Q99988

Gene Name

GDF15

Protein Tag

hFC Tag

Short Description

Recombinant Human GDF15 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala197-Ile308.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Price
£225.00


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