Cynomolgus GPRC5D Protein-VLP (GPR-CM05P)
Catalogue Number: GPR-CM05P-KAT
GPR-CM05P Image
GPR-CM05P Image
GPR-CM05P Image
The purity of Cynomolgus GPRC5D VLP is greater than 95% as determined by SEC-HPLC.
GPR-CM05P Image
Immobilized Cynomolgus GPRC5D VLP (100 µl/well) at 5 µg/ml (100 µl/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.91 µg/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The target protein has a predicted MW of 35.10 kDa. |
| Physical state: | Liquid |
| Type: | Other Proteins |
| Alias: | GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug |
| Application: | ELISA |
Description
Description: Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer. The orphan G protein-coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Additional Text
Gene Name
GPRC5D
Gene ID
102122120
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
UniProt ID
A0A2K5W6I7
Short Description
Recombinant Cynomolgus GPRC5D Protein-VLP is expressed from HEK293.; It contains Met1-Cys300.
GPR-CM05P Datasheet
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