Catalogue Number: GTX00451-GTX
Manufacturer: | GeneTex |
Preservative: | 0.05% Sodium azide |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | syndecan 1 , CD138 , SDC , SYND1 , syndecan |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Mouse |
Clone: | 1A3H4 |
Isotype: | IgG1 |
Immunogen: | A recombinant fragment of human SDC1 (AA: 28-171) expressed in E. coli. |
Application: | ELISA, FACS, ICC, IF, IHC-P, WB |
Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
6382
SDC1
P18827
32
Affinity Purified
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
WB: 1:200-1:1000. ICC/IF: 1:200-1:1000. IHC-P: 1:200-1:1000. FACS: 1:200-1:400. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.