CD33 antibody [WM53]
Catalogue Number: GTX00477-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15mM Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CD33 , CD33 molecule , SIGLEC3 , p67 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | WM53 |
| Isotype: | IgG1 |
| Immunogen: | Human AML cells |
| Application: | FACS, ICC, IF, IP, WB, IHC-Fr, MS |
Additional Text
Concentration
1 mg/ml
Gene Name
CD33
Gene ID
945
Uniprot ID
P20138
Purification
Protein A purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
40
Short Description
CD33, also known as Siglec-3 or gp67, is a 67 kDa glycosylated cell surface receptor that mediates cell-cell interactions and maintains immune cells in a resting state. Although CD33 is found on some lymphoid subsets, it is highly expressed on myeloid lineage cells, and is commonly used for the diagnosis of acute myeloid leukemia (AML). CD33 is an established target for therapy, with CD33-positive blasts detected in almost 90 percent of patients presenting with AML.
GTX00477 Datasheet
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