PSMD2 antibody
Catalogue Number: GTX02394-GTX
GTX02394 Image
GTX02394 Image
GTX02394 Image
IP analysis of Jurkat whole cell lysate using GTX02394 PSMD2 antibody. IP antibody : 4 µl per 0.5 mg total whole cell lysate Dilution : 1:100 Immunomagnetic beads Protein A/G : 60 µg
GTX02394 Image
WB analysis of Jurkat whole cell lysate (Lane A) using GTX02394 PSMD2 antibody. Dilution : 1:500 Loading : 30 µg
| Manufacturer: | GeneTex |
| Preservative: | 0.03% ProClin 300 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | proteasome 26S subunit, non-ATPase 2 , P97 , RPN1 , S2 , TRAP2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide corresponding to the N-terminus of the Human PSMD2 |
| Application: | IP, WB |
Description
Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Additional Text
Gene ID
5708
Uniprot ID
Q13200
Molecular Weight
100
Gene Name
PSMD2
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Purification
Affinity Purified; Protein A Purified
Application Notes
WB: 1:500-1:2000. IP: 5-10 µl/mg of lysate. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX02394 Datasheet
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