Mesothelin antibody [MSVA-235M] HistoMAX™

Catalogue Number: GTX04373-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Molecular Weight:69
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:mesothelin , MPF , SMRP
Shipping Condition:Blue Ice
Unit(s): 100 ul, 500 ul
Host name: Mouse
Clone: MSVA-235M
Isotype: IgG2b
Immunogen: Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein
Application: IHC-P

Description

Description: This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Additional Text

Gene Name

MSLN

Uniprot ID

Q13421

Gene ID

10232

Molecular Weight

69

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Application Notes

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Price
£320.00


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