Melanoma gp100 antibody [MSVA-617R] HistoMAX™
Catalogue Number: GTX04382-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | premelanosome protein , D12S53E , ME20 , ME20-M , ME20M , P1 , P100 , PMEL17 , SI , SIL , SILV , gp100 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 500 ul |
| Host name: | Rabbit |
| Clone: | MSVA-617R |
| Isotype: | IgG |
| Immunogen: | Recombinant fragment of human SILV protein |
| Application: | IHC-P |
Description
Description: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
Additional Text
Gene ID
6490
Purification
Protein A/G Purified
Gene Name
PMEL
Concentration
0.2 mg/ml
Uniprot ID
P40967
Antibody Clonality
Recombinant Monoclonal
Application Notes
IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX04382 Datasheet
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