CD3 epsilon antibody [MSVA-003R] HistoMAX™

Catalogue Number: GTX04389-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Molecular Weight:23
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD3e molecule , IMD18 , T3E , TCRE
Shipping Condition:Blue Ice
Unit(s): 100 ul, 500 ul
Host name: Rabbit
Clone: MSVA-003R
Isotype: IgG
Immunogen: A synthetic peptide from human CD3e protein (around aa 20-40)
Application: IHC-P

Description

Description: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CD3E

Gene ID

916

Uniprot ID

P07766

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Recombinant Monoclonal

Molecular Weight

23

Application Notes

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Price
£320.00


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