S100 beta antibody [MSVA-490R] HistoMAX™
Catalogue Number: GTX04404-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | S100 calcium binding protein B , NEF , S100 , S100-B , S100beta |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 500 ul |
| Host name: | Rabbit |
| Clone: | MSVA-490R |
| Isotype: | IgG |
| Immunogen: | Recombinant full-length human S100B protein |
| Application: | IHC-P |
Description
Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
S100B
Gene ID
6285
Purification
Protein A/G Purified
Concentration
0.2 mg/ml
Uniprot ID
P04271
Antibody Clonality
Recombinant Monoclonal
Application Notes
IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX04404 Datasheet
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