Estrogen Receptor alpha antibody [MSVA-564R] HistoMAX™
Catalogue Number: GTX04474-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 500 ul |
| Host name: | Rabbit |
| Clone: | MSVA-564R |
| Isotype: | IgG |
| Immunogen: | Recombinant fragment (around aa495-595) of human ER alpha protein |
| Application: | IHC-P |
Description
Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Additional Text
Gene ID
2099
Gene Name
ESR1
Uniprot ID
P03372
Purification
Protein A/G Purified
Concentration
0.2 mg/ml
Antibody Clonality
Recombinant Monoclonal
Application Notes
IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX04474 Datasheet
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