Kallikrein 7 antibody [MSVA-707M] HistoMAX™

Catalogue Number: GTX04475-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Molecular Weight:28
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:kallikrein related peptidase 7 , PRSS6 , SCCE , hK7
Shipping Condition:Blue Ice
Unit(s): 100 ul, 500 ul
Host name: Mouse
Clone: MSVA-707M
Isotype: IgG2b
Immunogen: Recombinant human KLK7 protein
Application: IHC-P

Description

Description: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]

Additional Text

Purification

Protein A/G Purified

Gene ID

5650

Uniprot ID

P49862

Gene Name

KLK7

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Molecular Weight

28

Application Notes

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Price
£320.00


Find out about delivery

SUPPORT

outstanding technical support

PRODUCT

we offer a full product guarantee

DELIVERY

we offer free delivery to UK universities and non profit organisations