Catalogue Number: GTX04475-GTX
Manufacturer: | GeneTex |
Preservative: | 0.05% Sodium azide |
Molecular Weight: | 28 |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | kallikrein related peptidase 7 , PRSS6 , SCCE , hK7 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 500 ul |
Host name: | Mouse |
Clone: | MSVA-707M |
Isotype: | IgG2b |
Immunogen: | Recombinant human KLK7 protein |
Application: | IHC-P |
Description: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
Protein A/G Purified
5650
P49862
KLK7
0.2 mg/ml
Monoclonal
28
IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.