BRG1 antibody [MSVA-397R] HistoMAX™
Catalogue Number: GTX04486-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , BAF190 , BAF190A , BRG1 , CSS4 , MRD16 , RTPS2 , SNF2 , SNF2L4 , SNF2LB , SWI2 , hSNF2b |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 500 ul |
| Host name: | Rabbit |
| Clone: | MSVA-397R |
| Isotype: | IgG |
| Immunogen: | Recombinant fragment (around aa 190-400) of human SMARCA4 protein |
| Application: | IHC-P |
Description
Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Additional Text
Gene Name
SMARCA4
Gene ID
6597
Uniprot ID
P51532
Purification
Protein A/G Purified
Concentration
0.2 mg/ml
Antibody Clonality
Recombinant Monoclonal
Application Notes
IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX04486 Datasheet
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