Catalogue Number: GTX102474-GTX
Manufacturer: | GeneTex |
Preservative: | 0.01% Thimerosal |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | PYD and CARD domain containing , ASC , CARD5 , TMS , TMS-1 , TMS1 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 25 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Recombinant protein encompassing a sequence within the center region of human TMS1. The exact sequence is proprietary. |
Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
1 mg/ml
29108
PYCARD
Q9ULZ3
Affinity Purified
Polyclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
22
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.