CD10 antibody [N2C1], Internal

Catalogue Number: GTX111680-GTX

Manufacturer:	GeneTex
Preservative:	0.025% ProClin 300
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	membrane metalloendopeptidase , CALLA , CD10 , CMT2T , NEP , SCA43 , SFE
Shipping Condition:	Blue Ice
Unit(s):	100 ul, 25 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Recombinant protein encompassing a sequence within the center region of human CD10. The exact sequence is proprietary.
Application:	IHC-P, WB

Overview
Datasheets

Description

Description: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq]

Additional Text

Gene ID

4311

Gene Name

MME

Uniprot ID

P08473

Concentration

1.01 mg/ml

Purification

Affinity Purified

Molecular Weight

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX111680 Datasheet

GTX111680 Reference

Price

£285.00

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