Mib antibody
Catalogue Number: GTX128382-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.01% Thimerosal |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | mindbomb E3 ubiquitin protein ligase 1 , cg5841 , chunp6889 , fe47f05 , im:7148100 , mib , wu:fe47f05 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant protein encompassing a sequence within the N-terminus region of zebrafish Mib. The exact sequence is proprietary. |
| Application: | IHC-WM |
Description
Description: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It thereby participates in many processes regulated by the Notch signaling pathway, such as midline cell fate specification prior to germ layer formation, patterning of sensory cell differentiation in the ear, neurogenesis of the hindbrain and commitment to a secretory fate in the intestine. Essential for early embryonic development.
Additional Text
Concentration
1 mg/ml
Gene Name
MIB1
Purification
Affinity Purified
Molecular Weight
113
Gene ID
352910
Uniprot ID
Q804S5
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
IHC-Wm: 1:50-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX128382 Datasheet
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