Tau antibody
Catalogue Number: GTX130462-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.025% ProClin 300 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | microtubule associated protein tau , DDPAC , FTDP-17 , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Tau. The exact sequence is proprietary. |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr, IHC |
Description
Description: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq]
Additional Text
Gene Name
MAPT
Gene ID
4137
Uniprot ID
P10636
Concentration
0.47 mg/ml
Purification
Affinity Purified
Molecular Weight
79
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
Tau antibody detects Tau protein, a phosphorylated microtubule-associated protein with a predicted molecular weight of 79 kDa. Tau protein has six isoforms in humans generated from a single gene. Expression changes of these Tau isoforms are controlled during neuronal development and in various pathological conditions. Dysfunction of Tau is associated with neurodegenerative diseases including Alzheimer's disease and frontotemporal dementia.
GTX130462 Datasheet
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