RAP1A antibody

Catalogue Number: GTX13521-GTX

Manufacturer:GeneTex
Preservative:No preservative
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:C21KG , G22K , KREV1 , RAP1 , RAP1A , RAP1A, member of RAS oncogene family , SMGP21
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide corresponding to a portion of human Rap1a. Peptide differs from Rap1b by two residues.
Application: WB

Description

Description: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Additional Text

Gene Name

RAP1A

Uniprot ID

P62834

Gene ID

5906

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

21

Application Notes

WB: 1µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.