Catalogue Number: GTX13521-GTX
Manufacturer: | GeneTex |
Preservative: | No preservative |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | C21KG , G22K , KREV1 , RAP1 , RAP1A , RAP1A, member of RAS oncogene family , SMGP21 |
Shipping Condition: | Blue Ice |
Unit(s): | 50 ug |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Synthetic peptide corresponding to a portion of human Rap1a. Peptide differs from Rap1b by two residues. |
Application: | WB |
Description: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
RAP1A
P62834
5906
Affinity Purified
Polyclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
21
WB: 1µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.