RPS6 (phospho Ser235) antibody [9H270]

Catalogue Number: GTX15031-GTX

Manufacturer:	GeneTex
Preservative:	No preservative
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	RPS6 , S6 , ribosomal protein S6
Shipping Condition:	Blue Ice
Unit(s):	50 ul
Host name:	Rabbit
Clone:	9H270
Isotype:	IgG
Immunogen:	Synthetic peptide containing the sequence ...RRL[pS]SL... in which pS corresponds to phospho-serine at residue 235 of human ribosomal protein S6.
Application:	WB

Overview
Datasheets

Description

Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

6194

Gene Name

RPS6

Uniprot ID

P62753

Modification

Phosphorylated, Ser235

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

GTX15031 Datasheet

Price

£439.00

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Quantity
Unit Size

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