alpha Actinin 4 antibody [7H6]
Catalogue Number: GTX15648-GTX
GTX15648 Image
GTX15648 Image
GTX15648 Image
GTX15648 Image
GTX15648 Image
IHC-P analysis of human colon carcinoma tissue using GTX15648 alpha Actinin 4 antibody [7H6]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:200
GTX15648 Image
IHC-P analysis of human kidney tissue using GTX15648 alpha Actinin 4 antibody [7H6]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:200
GTX15648 Image
IHC-P analysis of human tonsil tissue using GTX15648 alpha Actinin 4 antibody [7H6]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:200
GTX15648 Image
WB analysis of samples using GTX15648 alpha Actinin 4 antibody [7H6].
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | actinin alpha 4 , ACTININ-4 , FSGS , FSGS1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 7H6 |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide corresponding to residues A(884) P Y Q G P D A V P G A L D(897) of human alpha Actinin 4. |
| Application: | ELISA, FACS, ICC, IF, IHC-P, WB |
Description
Description: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
Additional Text
Concentration
1 mg/ml
Gene Name
ACTN4
Uniprot ID
O43707
Gene ID
81
Purification
Protein G purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
105
Application Notes
WB: 2 µg/mL. ICC/IF: 4 µg/mL. IHC-P: 4 µg/ml. FACS: 1µg per 10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX15648 Datasheet
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