Melanoma gp100 antibody [PMEL/2037]

Catalogue Number: GTX17772-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	D12S53E , ME20 , ME20M , P1 , P100 , PMEL , PMEL17 , SI , SIL , SILV , gp100 , premelanosome protein , Pmel 17
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	PMEL/2037
Isotype:	IgG1
Immunogen:	A recombinant fragment (around aa 376-502) of human SILV protein (exact sequence is proprietary)
Application:	ELISA, IHC-P, PA

Overview
Datasheets

Description

Description: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

Additional Text

Purification

Protein A/G Purified

Gene Name

PMEL

Concentration

0.2 mg/ml

Uniprot ID

P40967

Gene ID

6490

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Application Notes

IHC-P: 1-2µg/ml for 30 minutes at RT. ELISA: 2-4µg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX17772 Datasheet

Price

£465.00

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Quantity
Unit Size

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