Hepatitis C virus NS4A protein antibody [5D4/10E7]

Catalogue Number: GTX19048-GTX

Manufacturer:GeneTex
Preservative:No preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Hepatitis C Virus Non-structural protein 4A , Hepatitis C Virus NS4A , HCV Non-structural protein 4A , HCV NS4A
Shipping Condition:Blue Ice
Unit(s): 250 ug
Host name: Mouse
Clone: 5D4/10E7
Isotype: IgG1
Immunogen: Synthetic peptide (Human) in which overlapping sequences of at least 90 residues in length were selected from the immunodominant NS4 regions of Chinese HCV strains.
Application: ELISA, IHC-P, WB

Description

Description: HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.

Additional Text

Concentration

1 mg/ml

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ELISA: Use at an assay dependent dilution. IHC-P: The dilution fold should be from 1:100 to 1:1000. WB: Use at a concentration of 0.5 µg/ml to detect 0.5 µg/lane of synthetic NS4 peptide and 0.1 µg/lane recombinant chimeric HCV polyprotein. Optimal dilutions/concentrations should be determined by the end user.